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Investors believe it's a $1-billion-to-$3-billion-a-year market, but hard figures are elusive, because most peptides are sold on the quasi-legal gray market

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For example, overexpression of OsGSTU5 gene improved the tolerance of rice to toxic heavy metal ion arsenic and effectively limited the upward transport of arsenic within the plant [13].The GST genes of Hordeum vulgare , Populus trichocarpa , Vitis vinifera , Camellia sinensis , and other species were overexpressed in Arabidopsis , and the growth status and physiological indicators of transgenic plants under salt, drought, and temperature stresses were better than those of wild type Arabidopsis [14,15,16,17,18,19]

Another example where GCLC and GS are coordinately regulated but GCLM is unchanged is found in liver-specific retinoid X receptor (RXR) knockout mice (Wu et al., 2004)