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The clinical trial protocol used a gradual dose escalation to minimize GI side effects: Most users inject into the abdominal area, rotating sites with each injection

These involve symptoms like new-onset bowel or bladder dysfunction, saddle anesthesia, and increased weakness in the lower extremities

Gastroenterology, 134(1), 166178

[18] [19] In males, prolonged HCG use may lead to gynecomastia due to increased aromatization of testosterone to estradiol

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