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Nicotine is addictive, and once people stop using products that contain this substance, they may However, by quitting cold turkey, the body expels all nicotine within 48 hours

In previous studies, participants used first-generation cartridge-based e-cigarettes, while in the present study, they were given second-generation refillable e-cigarettes and free choice of e-liquids, the authors noted

Environ Toxicol Pharmacol (2016) 45:809.10.1016/j.etap.2016.05.016 18 WangHMaLLiYChoCH

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Principal study author Allan Hackshaw, deputy director of the University College London Cancer Trials Centre, said he was personally motivated to conduct this study given his many friends and family members who have cut back on -- but not quit -- their smoking habits