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Microbial metabolite butyrate facilitates M2 macrophage polarization and function

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Cureus, 17(1), e78045

For example, while cytosolic and mitochondrial superoxide dismutase (SOD1 and SOD2) were more abundant in tumor tissue (especially the mitochondrial isoform SOD2), SOD3, the excreted isoform, was significantly more abundant in healthy tissue (Fig