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Apparent kinetic rate ( k app ) reflects the rate of observed VitC signal change caused by both T 1 relaxation and VitC production from DHA, while k reflects only the VitC production rate

J Cereb Blood Flow Metab 37:21122124

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

*Correspondence: Kate Worster, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Artesunate may inhibit the proliferation of lung cancer cells, downregulate the expression of anti-apoptotic molecules Bcl-2 and survivin, upregulate the expression of pro-apoptotic molecules P53 and Bax, and increase the activity of caspases and apoptosis rate through the PPAR-/TGF-1/Smad2/3, AKT/Survivin, P38/JNK/ERK, and MAPK pathways (Pan et al., 2021