Enzymes then recycle GSSG back to GSH using energy from NADPH
Results: scRNA-seq analysis revealed that a subset of MDMs expressed tissue restoration-related genes ( Arg1 , Il10 , and matrix metalloproteases), referred to as restorative MDMs, which highly expressed Slc7a11 encoding the cystine/glutamate antiporter (xCT) in both mouse and human

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bulgaricus LB42: From preclinical safety assessment to clinical evidence
This study provides an early report of the loss of glial cells within the PFC of patients with mood disorders, consistent with the hypothesized glutamate abnormalities in these disorders