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Therefore, carnitine participation in redox signaling and affecting transcription factors (Nrf2, PPAR, NF-B, etc.) as well as activating the vitagene network are main mechanisms responsible for the antioxidant action of LC and its derivatives

Acetyl L-Carnitine is a high-quality supplement that contains a natural amino acid that is essential for the production of energy and the metabolism of fats

Mingorance C, et al

Mazahery H, Conlon CA, Beck KL, Mugridge O, Kruger MC, Stonehouse W, et al

This raises questions about cortical involvement and highlights the need for preclinical studies to clarify underlying mechanisms, given the limited accessibility of early-stage, untreated brain tissue from SMA patients