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Q6: What are the reported side effects of DSIP

A feedback inhibition by cysteine decreased SERAT1;1 and -3;1 activity but appeared to have no impact on the three other SERAT isoforms (Figure 2 and Supplementary Table 2

Hypotaurine can cross the BBB, which sets it apart from most hydrophilic molecules including GABA

A larger clinical trial randomly assigned more than 500 patients with type 2 diabetes and symptomatic peripheral neuropathy to one of the following treatments: (i) 600 mg/day of intravenous lipoic acid for three weeks followed by 1,800 mg/day of oral lipoic acid for six months, (ii) 600 mg/day of intravenous lipoic acid for three weeks followed by oral placebo for six months, or (iii) intravenous placebo for three weeks followed by oral placebo for six months (76)

And it was just fun to go back and forth with Andy