Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide The activities of SNAP-tag and

The activities of SNAP-tag and H5 enzymes on BGSN3 are reasonable (IC50=17

Induced degradation of SNAP-fusion proteins

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C48H77N9O18 Molecular Weight 1068

383 SMILES OCCOCCCC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DOTA bifucational chelator containing a carboxylic acid group

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide The activities of SNAP-tag andSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine