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doi: 10.1155/2018/2424586 16 NilssonBEkdahlKNKorsgrenO

These mechanisms of action encompass both direct interventions on cancer cells and indirect modulation of the tumor microenvironment, potentially leading to apoptosis, autophagy, or necroptosis

The prostate surrounds the urethra

Furthermore, although CsA is a well-known inhibitor of the mitochondrial permeability transition pore through blocking cyclophilin D [54], examination of its immediate effects on mitochondrial function showed only marginal changes (Additional file 1: Fig