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2177-A FATTY ACID DESATURASE 2 rs174583 GENETIC VARIANT IS INVOLVED IN ADVANCED FIBROSIS IN FATTY LIVER DISEASE Shunsuke Ikejima, Kazuyoshi Kon, Kumiko Arai, Akira Uchiyama, Hiroo Fukada, Kyoko Fukuhara, Reiko Yaginuma, Toshifumi Sato, Maki Morinaga, Masahiro Tada, Hisafumi Yamagata, Hironao Okubo and Kenichi Ikejima, Juntendo University School of Medicine Background: Genetic factors are deeply involved in the pathological progression of nonalcoholic fatty liver disease (NAFLD) and alcohol-associated liver disease (ALD)

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