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At the end of the study period, stability in peritoneal membrane transport parameters and dialysis adequacy were observed

add 0.5ml (50units) DMSO, add slowly and gently swirl until dissolved

These models demonstrate the distinct temporal and pathological progression of AD ike features, including tau abnormalities, intraneuronal A accumulation, and synaptic and neuronal loss, making them valuable tools for studying disease mechanisms and therapeutic strategies