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Mice lacking MLCK210, although may develop GVHD in a Major-Histocompatibility Complex (MHC) mismatched transplant setting, are protected from prolonged intestinal barrier loss and severe GVHD, as shown by reduced tissue damage, decreased number of CD8 + T cells in the gut, and better overall survival [111]

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Control groups received scopolamine or aCSF 20 min prior to testing followed by aCSF 10 min prior testing