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This mutation, along with changes in membrane fluidity and gene expressionsuch as the upregulation of genes related to surface proteins and phosphoglycan biosynthesis, and the downregulation of stress response and folate transport geneshighlights specific genetic and metabolic adaptations rather than a general resistance profile

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Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches

KEGG pathway enrichment analysis was employed to explore the potential functions of DEGs and the core drought-responsive genes in the two genotypes under drought stress at 36 and 72 h