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It may enhance glucose uptake in cells and reduce symptoms of diabetic peripheral neuropathy, though evidence is strongest for intravenous administration, with more modest and uncertain benefits from oral supplementation

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E-selectin/CD62/or endothelial-leukocyte adhesion molecule 1 is a key adhesion factor expressed in activated endothelium, which is involved in recruitment of leukocytes, particularly neutrophils during tissue injury 36