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As emphasized in this review, the integration of advanced computational tools, particularly machine learning and artificial intelligence, has greatly enhanced the analytical power of metabolomics, enabling the extraction of predictive biomarker panels and individualized treatment profiles from high-dimensional datasets

rather, it induces an amino acid starvation response by upregulating the expression of SLC38A1, suggesting that SLC38A1 is a major importer of glutamine into these cells 90

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