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Polyphenols can promote memory, learning and cognitive abilities by protecting neurons and inhibiting neuroinflammation

However, findings about Clostridium genus abundance remain inconsistent [27]

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Briefly, the mTORC1 promotes LDHA/PKM2 expression by activating HIF-1 and catalyzes the reductive carboxylation of glutamine to generate lipid synthesis precursors, thus exacerbating synovial inflammation ( A study showed that inhibiting PFKFB3 could selectively block Th17 metabolism ( Table 1 )