e3 ubiquitin ligases mitophagy copd smoking or cigarette smoke Dysregulated autophagy in COPD: A pathogenic process to be deciphered PRKN Ser131 phosphorylation promotes cigarette

PRKN Ser131 phosphorylation promotes cigarette smoke induced mitophagy impairment and epithelial cell senescence via MKK3 p38 MAPK activation: An in vitro and in vivo study Full article: Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease Cigarette smoke induced impairment of autophagy in macrophages increases galectin 8 and inflammation Scientific Reports The effects of epithelialmesenchymal transitions in COPD induced by cigarette smoke: an update Respiratory Research Springer Nature Link Targeting E3 ubiquitin ligases and their adaptors as a therapeutic strategy for metabolic diseases Experimental & Molecular Medicine

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