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The CFAX12 platform, therefore, proves to be an essential tool for preclinical research, enabling detailed exploration of the cellular and molecular mechanisms underlying cigarette smoke-related diseases and facilitating the development of targeted therapeutic strategies

In addition, advances in early detection and treatment have further served to reduce the death rate

Smoking-Related Molecular Mechanisms At present, the pathogenesis of AAA is mainly attributed to inflammatory cell infiltration, the destruction of elastin and collagen in the media and adventitia, biological changes in smooth muscle cells and angiogenesis (180, 181)

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In fact, cigarette smokers are 30 to 40% more likely to develop type 2 diabetes than non-smokers are