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Prevalence and outcome under thyroid hormone therapy

J Natl Cancer Inst 107(7), 2015

MMP-2, which often acts with MMP-9, degrades the ECM and basement membrane, promoting EMT and enhancing cancer invasiveness [343]

Du K, Ramachandran A, Jaeschke H

Notably, tyrosinase possesses two copper ions, i.e., CuA and CuBcoordinate with six histidine (His) residues in the conserved catalytic pocket 14,15 , and are critically required to exhibit both types of enzymatic activities 6,16