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Similarly, no significant changes in LINE-1 and Alu methylation among female nurses was observed, although several gene-specific hypomethylation effects to the estrogen receptor gene ESR1 (associated with heightened estrogen sensitivity), to the tumor suppressor genes TP53 and BRCA1 (indicating possible disruption in cell cycle regulation and DNA repair mechanisms) were reported

Long-term studies show additional benefits

UV radiation increases oxidative stress and skin cancer risk, but medicinal plants especially those used in Traditional Chinese Medicine offer photoprotection by modulating key cellular pathways

One notable advantage of tissue-specific cell-derived EVs is their natural homing ability to specific sites 209