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Low dose naltrexone for induction of remission in Crohns disease doi: 10.1002/phar.2086

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In a second study by this group, 16 adult rhesus monkeys were assessed for hypertensive status using cutoffs for systolic and diastolic BP of 120 mm Hg and 80 mm Hg, respectively, a protocol that is suitable for use in non-human primates [104]

Depletion of adenosine has been shown to reduce fibrosis, inflammation, and vasculopathy in two preclinical mouse models of SSc 61