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281 SAM and superoxide dismutase 1 (SOD1) can synergistically counteract the exacerbation of AD-like features caused by B-vitamin deficiency, suggesting that the combination of SAM and SOD1 may serve as a potential adjunctive therapy for AD

A total of 98 G6PD-associated genes were identified, and out of the 47 implicated signaling pathways, seven were highly likely to be regulated by G6PD-associated genes