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In addition, they may have other modes of action, as causing oxidative stress, genetic susceptibility, and epigenetic modifications (e.g., DNA methylation, miRNA) (62, 63), ultimately resulting in gene expression changes (62, 64, 65) in particular when exposure occurs during prenatal and early postnatal life

trichocarpa , there are 54 GSTU and 8 GSTF isoforms

Key Functions of Glutathione Antioxidant Defense : Glutathione is a powerful antioxidant that helps neutralize free radicals, reducing oxidative stress in cells

J Biol Chem 267:1986619871 Wilce MCJ, Parker MW (1994) Structure and function of glutathione S-transferases

10.1007/s002849900148 83