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Detailed Category Analysis# Mechanism of Action# Mazdutide : GLP-1/glucagon dual receptor agonist designed as an oxyntomodulin analog

Observation periods included the in-trial period (that is, while in the trial, regardless of treatment discontinuation or rescue intervention) and the on-treatment period (with trial product)

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20,29,32,37,43 Consistently, castration, ARPIs, chemotherapeutic drugs, prooxidants and radiation have all been reported to induce BCL-2, which in turn promotes PCa cell survival and resistance to such agents

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