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It is also recognized that smoke exposure leads to the activation of the Nod-like receptor protein 3 (NLRP3) inflammasome [63], with consequent local generation of active interleukin 1 (IL-1), a process that induces inflammation and thereby can lead to both chronic fibrosis and cancer in mice [64]

The close friend of both Camilla and Charles is the daughter of Lady Susan Hussey, who served as the late Queens lady-in-waiting for more than 60 years