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4.8
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Description

S1406: Randomized phase II study of irinotecan and cetuximab with or without vemurafenib in BRAF-mutant metastatic colorectal cancer (mCRC)

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The SER is a prominent constituent of some cells, especially the cells in the adrenal cortex (which secrete steroid hormones), the cells of the liver (hepatocytes), where it makes lipids for secretion of lipoproteins, and the sarcoplasmic reticulum of muscle cells

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USA 104 , 1126811273 (2007)

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Dosing, timing, and administration methods for both compounds are subjects of extensive debate and depend entirely on the research model and objective

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