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In reviews of the literature published between 1999 and 2007, Daly-Youcef [4] and Andrs E [19] concluded that orally administered vitamin B12 provided effective treatment for adult and elderly patients with deficiencies, although they highlighted that further studies were needed to determine its effectiveness in patients with severe neurological symptoms

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Studies show that oral vitamin B12 absorption can be as low as 12% in people with digestive issues, aging-related changes, or certain medications