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409 AQP9 deficiency not only disrupts glucose metabolism, but also disrupts the transport of H 2 O 2 , a crucial signal in the livers proliferative phase

References Bousso, P

As expected, the serum total IgG levels in saline treated mice was significantly (p value less than 0.001) higher than control untreated mice

GST-tagged Ly49Q deletion mutant proteins were collected from BL21 Rosetta cell soluble fractions using glutathione-Sepharose 4B columns according to the manufacturers instructions (Thermo Fisher Scientific) and eluted with 10 mM reduced glutathione in 50 mM Tris pH 8.0

In the future, further mechanistic studies are need to fully elucidate how APAP manages to alter metabolic flux, which proteins it binds and why the cells are driven into an enhanced Warburg effect