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To provide further compelling evidence that SP inhibits the cGAS-STING pathway by suppressing the release of mtDNA, we employed EtBr at a concentration of 1.0 g/mL for 48 h to block mtDNA replication, which contributed to a reduced copy number of ND1 and ND2 , confirming the successful depletion of mtDNA (Figure 7F, G)

Laboratory analyses were performed at Ivano-Frankivsk National Medical University, the Centre for Bioelementology of IFNMU, and the Centre for Infectious Diseases as part of routine medical and diagnostic work

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Overview of Metabolic Demands in Immunity In principle, the regulation of cellular metabolism is coordinated with energy demands and to fulfill biosynthetic, and redox control processes within cells

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