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Combined therapy with gaba and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting beta-cell replication in newly diabetic nod mice

Degenfeld-Schonburg L, Gamperl S, Stefanzl G, Schruef AK, Sadovnik I, Bauer K, et al

Therefore, the authors suggest that TOS and TAS levels may serve as additional markers for the diagnosis and assessment of the clinical severity of NVP

Published July 15, 2025

The exact mechanism of eNOS modification is unknown but in vivo experiments have shown that eNOS activation in aortas and iNOS transgenetic expression in mouse heart both result in NO-induced protein S-glutathionylation