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Noteworthy, the vaccine that contains 100 g should be stored at 20 C, while the vaccine with only 30 g mRNA should be strictly kept at 70 C

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Notably, specific strains, such as Bifidobacterium pseudolongum, excessively proliferate and disrupt the barrier in Allergin-1-deficient mice, while neomycin can reverse this effect, indicating that immune receptors influence barrier function by modulating the microbiota composition [111]