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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

Key takeaways Vitamin B12 shots are injections that a doctor may prescribe to treat a vitamin B12 deficiency

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Macrocobalamin, or macro-B12 Macro-B12, also called macrocobalamin, is B12 bound up in large complexes, most often with antibodies or carrier proteins, that the assay still counts toward the total