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ERK1/2 activation is often triggered by growth factors, particularly vascular endothelial growth factor (VEGF), a key driver of angiogenesis

The peak area of the LC-UV signal at 229 nm with retention time 8.87 min (desulfo-4MSOB-GL) was used for quantification of 4MSOB-GL with reference to the signal of the internal standard, sinalbin (in the form of desulfo-sinalbin), using a response factor of 2 27

For a deeper explanation, you can also watch our short video on why opioids increase pain sensitivity and how ketamine resets the system

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