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While islets of donors with type 2 diabetes do not display reduced expression of PC1/3 (also known as PCSK1 ) and/or CPE mRNA [33, 78], one study found that palmitate treatment of islets isolated from non-diabetic deceased organ donors reduced CPE protein levels [79]

Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome

(92) suggested that drug administration such as intravitreal injection of lipid peroxides induces posterior subcapsular (PSC) cataract in a rabbit-eye model

However, further research in additional mouse models is necessary to understand the comprehensive effects of such molecular drugs on NAFLD [73]