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This work is partially supported by the National Cancer Institute (NCI) of the National Institutes of Health (NIH) (R01CA057341 (C.V.D)), The Leukemia and Lymphoma Society LLS 6106-14 (C.V.D.) and the Abramson Family Cancer Research Institute

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(2014) reported that at short-term, B deficiency affects cytosolic Ca 2+ levels, and in roots, upregulates the expression of genes from the MYB protein family involved in Ca 2+ signaling and represses genes of the bZIP protein family with roles as channels/transporters, sensor relays and responders that act as intermediaries in a transduction pathway triggered by B deficiency, with important consequences in plant development, growth, flower maturation and stress (Zhao et al., 2021b)