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TB-500 distributes systemically regardless of injection location due to its longer half-life and different distribution characteristics

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Bibcode:2021Sci...374.1586O

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Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively