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A.AgarwalaP.SpieglerP.DeleonJ.et al (2022)

Interestingly, one study reported that GCN2 is dispensable for T cell anti-tumor activities in murine melanoma models, as T cell-specific GCN2 knockout neither impairs T cell responses against tumors, nor does it significantly affect FoxP3 expression in CD4+ T cells or IFN- expression in both CD4+ and CD8+ T cells in the tumor