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injection-site discomfort (redness, itching, slight swelling) The majority of these occur while the body is adjusting, the dosage is excessive, or there is insufficient hydration

longer-term data will follow

It is important to note that this mechanism, while biologically plausible, is not yet validated by large-scale controlled trials, and individual results vary considerably depending on baseline melanin levels, skin type, and dosage

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Even if short-term studies report no safety concerns, they would not be designed to detect longer-term risks like cancer or abnormal tissue growth, which may take years to emerge