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A study conducted by Boland et al

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280 Pharmacological selenium significantly reduces infarct volume by driving an adaptive transcriptional program to block ferroptosis

Furthermore, flavonoids modulate second messenger pathways (e.g., cGMP, cAMP, calcium) to reduce the production of inflammatory mediators, such as PGs and ILs, and inhibit the activity of enzymes like COX and lipoxygenase (Naoi et al., 2019)