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It's associated with a range of health risks, including neurodegeneration, mitochondrial dysfunction, impaired detoxification, toxin accumulation, malignancy, and increased antioxidant need

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Glucose-6-Phosphate Dehydrogenase Deficiency (which will be covered primarily in the hematology section) is a deficiency of a key enzyme in the pentose phosphate shunt that limits the creation of NADPH

High visceral fat percentage is associated with poor outcome in endometrial cancer

Maraganore DM, Lesnick TG, Elbaz A, Chartier-Harlin MC, Gasser T, Krger R, Hattori N, Mellick GD, Quattrone A, Satoh JI, Toda T (2004) UCHL1 is a Parkinson's disease susceptibility gene