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Eukaryotic cells, for example mammalian host cells, yeast or filamentous fungi, are preferred, and in particular mammalian cells, because they are more likely than prokaryotic cells to assemble and secrete a properly folded and immunologically active antibody

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Melasma is different from sun spots: Melasma is hormonally driven and can be worsened by aggressive laser treatment

In the HepG2 fatty liver cell model, hypoxia-inducible factor-2alpha (HIF-2)/PPAR pathway was found to be essential for Lira to inhibit liver lipid synthesis and reduce lipid-induced hepatic steatosis [57]

Ryan BJ, Wachsmuth NB, Schmidt WF, et al