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In MCAS, mast cells lose their regulatory mechanisms and begin to "degranulate" (burst open) inappropriately in response to benign triggers like certain foods, temperature changes, or even emotional stress

Engineering and delivery of cGAS-STING Immunomodulators for the immunotherapy of Cancer and autoimmune diseases

(1) Flavonoids: Baicalein mainly exists in the roots of Scutellaria baicalensis and Scutellaria lateriflora

Blood brain barrier (BBB) is one of the main hurdles in developing drugs against various neurological disorders, as most of the compounds with high molecular weight cannot cross and attenuate BBB (Akhtar et al., 2021