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All chronic diseases, including COVID-19 with the long-COVID-19-syndrome (271), are characterized by the presence of persistent chronic inflammation and sustained generation of reactive oxygen and nitrogen species that when confronted with inadequate antioxidant defenses (likely leading components of anti-inflammaging) precipitate excessive oxidative stress

Further, she had hemolytic anemia and was transfused with suspended red blood cells to correct this condition

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Nature 582 , 129133 (2020)

During seasonal transitions, the bodys nutritional requirements may fluctuate