L-glutathione reduced, vitamin E (D-alpha tocopheryl acetate), L-lysine, anti-caking agent: magnesium salts of fatty acids
According to the results of studies revised and discussed in this paper, we identify the following highlights: (i) The low solubility and poor bioavailability of I3C and DIM limit their use as a medical treatment, so it is necessary to increase the research regarding pharmaceutic forms that improve these parameters, (ii) I3C and DIM have pro-apoptotic and antiproliferative effects and inhibit cell growth in pre-clinical and clinical cancer assays (Tables 2 and 3), (iii) Since I3C and DIM derivatives such as 5,5-Br2-DIM, the regulated cellular process associated with hallmarks of cancer, it could be essential to evaluate also these derivatives as anti-cancer agents, maybe in conjunct with DIM or I3C, and finally, (iv) The current evaluation of the anti-tumoral activities of DIM and I3C is generally based on mechanisms involving signalizing ways such as NF- B, Akt, Wnt, PI3K/Akt/mTOR, and AhR
In aquaculture, beneficial feed additives such as probiotics and prebiotics are utilized to stimulate growth, enhance immunity to combat diseases, and provide alternative antimicrobial solutions ( According to Wee et al
The past years have seen significant progress in the development of GLS inhibitor, BPTES, as a promising drug candidate by researchers
Inhibiting the NF-B signaling pathway and activating the PI3K/AKT signaling pathway are essential for these effects (199201)
