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Walter F, Schmid J, Dussmann H et al (2015) Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival

Ding et al., 2024)

Treatment of cells Hepatoma HepG2 cells were maintained in DMEM (GE Healthcare, Buckinghamshire, UK) supplemented with 10% fetal bovine serum (FBS), 100 U/ml penicillin and 100 g/ml streptomycin at 37 C in 5% CO 2

In another study, Liu et al

In rats with traumatic brain injury, KD treatment led to increased protein levels of NAD(P)H: quinone oxidoreductase 1 (NQO1), SOD1, and SOD2 in cortical homogenate, which prevented mitochondrial dysfunction mediated by oxidative stress [47]