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VR for ADA+ vs ADA patients was similar at BLV 2 mg (ADA+, 10/15 [67%] vs ADA, 34/49 [70%]) and higher with BLV 10 mg (ADA+, 13/14 [93%] vs ADA, 38/50 [76%]), respectively (Table)

The DSIP-CBBBP group, in particular, showed superior improvement over both the model and DSIP-only groups, suggesting enhanced efficacy of the fusion peptide

On the other hand, nonhomologous end joining is a repair process that is prone to errors and does not require a matching template

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