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A most striking difference from the mammalian glutathione S-transferases, which share a conserved catalytic tyrosine residue, is the lack of this tyrosine in the active site of the plant glutathione S-transferase

3a, b, and Supplementary Fig

HBV-DNA integration is detected in 86% of HBV-related HCC tumor cells [4]

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Compound 2 which is a chromen-based compound, (PubChem ID: STK610045) emerged as the lead molecule, exhibiting potent and selective cytotoxicity against TNBC cell lines, particularly MDA-MB-468 (IC 50 = 9.46 M) and MDA-MB-231 (IC 50 = 18.30 M), while sparing normal prostate epithelial cells (PNT2), indicating a favourable selectivity index