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Targeting PI3K/Akt signaling pathway In pre-clinical studies, phosphatase and tension homolog is acknowledged as a negative regulator of the PI3K/Akt pathway in PH treatment 190 (Table 1)

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2-[[3-(1,3-Benzodioxol-5-yl)-1-oxopropyl]amino]-N-(2,6-dimethylphenyl)-6-benzothiazolcarboxamid

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