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Besides, glutamate serves as a primary substrate for ROS generation [30, 31], and we noticed that glutamate accumulation increased intracellular ROS in cystine-starved T cells (Fig

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These effects were further reconfirmed by the electron microscopic study of brain which showed discontinuous myelin sheath around the axon including swollen mitochondria, blebbed nucleus as well as nuclear membrane changes with the treatment of mercuric chlo- ride

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